The Biology of Ageing: From Growth Signals to Cellular Resilience

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About Course

This course explores the core biology of ageing, focusing on how growth, repair, and resilience pathways shape cellular health over time. You will gain a clear, practical understanding of key longevity mechanisms and how they influence long-term wellbeing. 
Estimated learning time: 1–2 hours, depending on your pace. 

What Will You Learn?

  • The roles of mTOR and AMPK in growth and energy regulation
  • How sirtuins and NAD⁺ support cellular repair and resilience
  • The impact of cellular senescence on ageing and tissue function
  • How stress responses influence long-term health
  • The role of epigenetic changes in shaping the ageing process
  • Understanding the balance between growth, repair, and longevity

Course Content

Module 1: The Control Switches: mTOR & AMPK
Welcome to Module 1: The Control Switches - mTOR & AMPK, part of The Biology of Ageing: From Growth Signals to Cellular Resilience course by Levitas Academy. In this module, we’ll explore how two master pathways - mTOR, the growth switch, and AMPK, the energy sensor, regulate the balance between building and repairing cells. You’ll learn how these pathways sense nutrients, respond to energy availability, and determine whether the body prioritises growth or restoration. By understanding how mTOR and AMPK influence longevity, metabolism, and repair, you’ll gain insight into how lifestyle factors such as fasting and nutrient intake can shape the biology of ageing.

  • Course Content
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  • Quiz Questions

Module 2: The Guardians of Repair: Sirtuins & NAD⁺
Welcome to Module 2: The Guardians of Repair - Sirtuins & NAD⁺, part of The Biology of Ageing: From Growth Signals to Cellular Resilience course by Levitas Academy. In this module, we’ll delve into how sirtuins, the body’s cellular repair crew, depend on NAD⁺ to maintain DNA stability, mitochondrial efficiency, and stress resistance. You’ll explore how these molecular mechanisms protect against age-related damage and why declining NAD⁺ levels reduce resilience over time. By understanding how NAD⁺ fuels repair and how boosting it can restore cellular health, you’ll gain a clearer view of how to support energy, repair, and longevity at the molecular level.

Module 3: Cellular Ageing, Senescence & Stress Response
Welcome to Module 3: Cellular Ageing, Senescence & Stress Response, part of The Biology of Ageing: From Growth Signals to Cellular Resilience course by Levitas Academy. In this module, we’ll examine how cellular senescence, the process by which damaged cells stop dividing, contributes to ageing and inflammation. You’ll learn about the role of senolytics in clearing these “zombie cells,” how heat shock proteins and hormesis strengthen cellular resilience, and how the epigenetic clock measures biological age. By the end, you’ll understand how repair mechanisms, mild stress, and targeted interventions can reduce inflammation, improve function, and support healthier ageing.

Final Assessment
Demonstrate your understanding of cellular ageing and its regulatory mechanisms through a reflective, evidence-based written assessment. Completion of this task is required to earn your Levitas Academy CPD certificate.

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